After Peter Parker is bitten by a genetically altered spider, he gains newfound, spider-like powers and ventures out to save the city from the machinations of a mysterious reptilian foe.

A giant alien spider escapes from a military lab and rampages the city of Los Angeles. When a massive military strike fails, it is up to a team of scientists and one clever exterminator to kill the creature before the city is destroyed.

After a convoy of American soldiers disappears, a special ops team is deployed to rescue them. They soon encounter an army of gigantic scorpions, spiders and snakes that have come to Earth from another dimension.