Kannan, a poor man, moves to Chennai in search of a job. Circumstances force him to pretend to be the husband of Anjali, a rich woman. What happens next?

Shiva and Gautam are buddies and HR professionals in the same firm. Gautam’s insatiable thirst for wooing women, leads him to abuse a bank marketing call that Shiva receives. Madhu, a miffed friend of the woman in the receiving end, starts to taunt Shiva

Vijay, a young man, kills two influential men, who evaded punishment for their crimes. While trying to accomplish his next mission with his friends, Vijay is targeted by his sister, a police officer.

Karthick, a brave youth, prays to God for an adventurous life. One day, God tells him that his wishes are granted and his life will change for better or worse in another twenty-five days.

6 Athiyayam is an anthology with 6 parallel stories that are correlated and the climax of each story is revealed only in the finale.